Endocrine Abstracts

Background: Amongst hospitalised patients, hyponatraemia is the commonest electrolyte abnormality with reported prevalence of about 25%. Its association with mortality, morbidity and increased length of stay is well recognised, including adverse fracture risk and falls with mild hyponatraemia in elderly. We audited the management of hyponatraemia in inpatients in a University hospital setting.Methods: Over a 3-month period, amongst all in-patients, we id...

The finding of an adrenal incidentaloma warrants a careful diagnostic work-up to assess hormonal activity and potential malignancy. Current diagnostic algorithms depend largely on imaging studies, which is time-consuming, expensive and carries a health risk. Urinary steroid profiling using gas chromatography/mass spectrometry (GC/MS) might be a valuable diagnostic test for differentiating benign from malignant adrenal lesions, as adrenocortical carcinomas (ACC) often cause abn...

Introduction: The low incidence rate of adrenocortical carcinoma requires a multidisciplinary approach in which specialised surgery has an essential role as complete resection of the primary tumour is the only chance of cure.In order to improve patient care, insight into surgical results within the ACC population is essential. In 2007, a Dutch Adrenal Network Registry has been created encompassing care and outcome of patients treated for ACC in The Nethe...